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CALCITONIN, Polyclonal rabbit anti-human Catalog number: RP-4007-01 0.5 ml Concentrated IgG 2 mg/ml RP-4007-02 1.0 ml Concentrated IgG. 2mg/ml RP-4007-04 7.0 ml Prediluted for IHC IgG ~ 10µg/ml Description: Calcitonin is a 32-amino acid polypeptide hormone that is produced in human primarily by the parafollicular (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH) Calcitonin staining can detect C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Buffer: Total IgG is purified by Protein A column and is supplied in10 mM PO4, 150 mM NaCl, pH 7.4, 1% BSA 0.05% sodium azide. Host: Rabbit Reagent: Conc. antibody Storage: 2-8oC. Epitope: Not determined Species reactivity: Human, others not tested Immunogen: Synthetic peptide from human Calcitonin conjugated to carrier protein. Molecular weight of antigen: Positive control: Human thyroid or medulary carcinoma. Cellular localization: Cytoplasmic Application: Immunohistochemistry (IHC) 1:50-1:200 using polymer or streptavidin biotin system. For 30 minute at room temperature. The optimum dilution should be determined by the individual lab. General Reference: Holm, R, J Pathology, 158: 213-217, 1989 Limitation and warranty: Our warranty is limited to the actual price paid for the product. We are not liable for any property damage, personnel injury, time, effort or economic loss due to our product. MSDS: This product contains 0.05 % sodium azide as a preservative, appropriate care should be taken in handling. National Institute of Occupational Safety and Health has warning that sodium azide can react with lead, copper, brass or solder in the pluming system and forms hydrazoic acid in acidic condition. Discard with copious amount of water. Avoid skin and eye contact with all laboratory products. Use appropriate lab. gear, lab coat , gloves and safety glasses. Do not ingest any lab. products. This product is not approved for administration in human or animals. |
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