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CARCINOEMBRYONIC ANTIGEN (CEA), Polyclonal rabbit anti-human
Catalog number: RP-4005-01 0.5 ml Concentrated IgG 2 mg/ml RP-4005-02 1.0 ml Concentrated IgG 2mg/ml RP-4005-04 7.0 ml Prediluted for IHC IgG 8 µg/ml Description: CEA is highly glycosylated 180 kDa glycoprotein involved in cell adhesion. It is normally produced during fetal development and then re expressed in increased amounts in colorectal, gastric, pancreatic, lung and breast carcinomas. CEA measurement is mainly used as tumor marker to identify recurrence after surgical resection. Buffer: Protein A purified total immunoglobulin IgG in10 mM PO4, 200 mM NaCl, pH 7.4, 1 % BSA, 0.05% sodium azide. Host: Rabbit Reagent: Concentrated or prediluted antibody. Storage: 2-8oC. Epitope: Not determined Species reactivity: Human, others not tested. Immunogen: Human CEA purified from colon carcinoma. Positive control: Human colon cancer Cellular localization: Luminal membrane and Cytoplasmic Application: Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections. Dilute 1:100-1:200 using polymer or streptavidin ~biotin system for 30 mins at room temperature. The optimum dilution should be determined by the individual lab. Specificity and Reactivity: This antibody recognizes CEA n several tumor tissues. References: 1. Gold P, Freeman SO J exp. Med.121: 439 (1965) 2. Hammarstrom S, Semin Cancer Biol. 9: 67-81 (1999) -------------------------------------------------------------------------------------------------------- Limitation and warranty: Our warranty is limited to the actual price paid for the product. We are not liable for any property damage, personnel injury, time, effort or economic loss due to our product. MSDS: This product contains 0.05 % sodium azide as a preservative, appropriate care should be taken in handling. National Institute of Occupational Safety and Health has warning that sodium azide can react with lead, copper, brass or solder in the pluming system and forms hydrazoic acid in acidic condition. Discard with copious amount of water. Avoid skin and eye contact with all laboratory products. Use appropriate lab. gear, lab coat , gloves and safety glasses. Do not ingest any lab. products. This product is not approved for administration in human or animals. --------------------------------------------------------------------------------------------------------------------------------- |
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