MUC2, Polyclonal rabbit anti-human
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MUC2, Polyclonal rabbit anti-human Catalog number: RP-4013-01 0.5 ml Concentrated IgG 2 mg/ml RP-4013-02 1.0 ml Concentrated IgG 2 mg/ml RP-4013-04 7.0 ml Prediluted for IHC IgG ~8µg/ml Description: Mucin 2, oligomeric mucus/gel-forming, also known as MUC2, is a human intestinal mucin gene. This gene is expressed in colon, small intestine, colonic tumors, bronchus, cervix, gall bladder, and possibly other tissues. Mucins are high molecular weight glycoproteins having oligosaccharides attached to serine or threonine residue of the apomucin protein backbone by O-glycosidic linkages. This antibody stains normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate carcinoma. Buffer Total immunoglobulin IgG purified by protein A column in 10 mM PO4, 200 mM NaCl, pH 7.4, 1% BSA, 0.05% sodium azide Host: Rabbit Intended Use Immunohistochemistry (IHC) and Immunocytchemistry (ICC) Storage: 2-8° Immunogen: 23 amino acid MUC2 peptide Positive control: Human colon carcinoma, LS 174 T colon cancer cell line Cellular localization: Cytoplasmic, perinuclear staining of goblet cells. Species reactivity: Human, mouse, rat, others not tested. Application: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:100 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. For FFPE tissue sections high temperature antigen retriever (boiling tissue in 10 mM citrate buffer for 10 minutes) enhances the signal and may require further dilution of antibody.. The optimum dilution should be determined by the individual lab. General References
-------------------------------------------------------------------------------------------- Limitation and warranty: Our warranty is limited to the actual price paid for the product. We are not liable for any property damage, personnel injury, time, effort or economic loss due to our product. MSDS: This product contains 0.05 % sodium azide as a preservative, appropriate care should be taken in handling. National Institute of Occupational Safety and Health has warning that sodium azide can react with lead, copper, brass or solder in the pluming system and forms hydrazoic acid in acidic condition. Discard with copious amount of water. Avoid skin and eye contact with all laboratory products. Use appropriate lab. gear, lab coat , gloves and safety glasses. Do not ingest any lab. products. This product is not approved for administration in human or animals. --------------------------------------------------------------------------------------------------------------------------------- |
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